in Chemical Coordination and Regulation (Endocrine System) by

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  1. Hyposecretion of adrenal cortical hormones due to surgical removal or atrophy of adrenal cortex causes Addison’s disease.
  2. Its symptoms include:
  • Excessive loss of Na+, Cl
  • Increased K+ level in blood leads to arrhythmia, dehydration, blood pressure and cardiac output decreases.
  • Skin pigmentation increases (colour darkens) due to decreased levels of cortisol in blood and increase in ACTH.
  • Hypoglycemia is seen.
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