in Molecular Basis of Inheritance by

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Somatic mutation

Germline mutation


It takes place in somatic or body cells like skin, etc.

It takes place in germ cells likes sperms and eggs.


Occur only in a localized area.

Example: Liver cells

Affect the sex chromosome causing abnormalities such as Down’s syndrome, etc.


They are not passed on to the progeny.

They are passed on to the progeny and affect the future generations.


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