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1.
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It is the protein part of the enzyme composed of only amino acids.
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It is the non-protein organic part of the enzyme which is attached to the apoenzyme to form conjugate protein.
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2.
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It is heat sensitive i.e. Thermolabile.
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It is heat stable.
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3.
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It is larger in size.
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It is smaller in size.
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4.
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It is specific for an enzyme.
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It can function as a cofactor for a number of enzymes carrying out specific functions.
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5.
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It is responsible for catalytic activity of the enzyme.
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It takes part in the removal of the products of the reaction.
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