When normal cells are transformed into cancer cells they show the following characteristics:
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Nucleus enlarges and has an irregular outline.
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Number of ribosomes increase.
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Mitochondria are swollen and irregular shaped
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Nucleolus is also enlarged and has unstable number of chromosomes.
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Cytoskeletal actin filaments decrease due to which the cell surface protein becomes mobile.
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Golgi complex is poorly developed.
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Cytoplasm has many inclusions. E.g. eosinophilic granules in leukemia, milk droplets in mammary tumour.
